Number of amino acids: 607
Molecular weight: 69692.1
Theoretical pI: 6.08
Total number of negatively charged residues (Asp + Glu): 97
Total number of positively charged residues (Arg + Lys): 87
Carbon C 3119
Hydrogen H 4876
Nitrogen N 826
Oxygen O 912
Sulfur S 36
Formula: C3119H4876N826O912S36Total number of atoms: 9769
Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.
Ext. coefficient 52895
Abs 0.1% (=1 g/l) 0.759, assuming ALL Cys residues appear as half cystines
Ext. coefficient 50770
Abs 0.1% (=1 g/l) 0.728, assuming NO Cys residues appear as half cystines
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
The instability index (II) is computed to be 40.99
This classifies the protein as unstable.
Aliphatic index: 82.31
Grand average of hydropathicity (GRAVY): -0.370